Heart Disease

 PhotoBioModulation has shown tremendous promise in treating heart disease, including  post-myocardial infarction heart failure.  Myocardial infarction is one of the common causes of heart failure. Myocardial reperfusion is currently the most effective and widespread therapy to reduce the effects of myocardial infarction and restore cardiac performance, however, it still results in a high level of morbidity and mortality. PhotoBioModulation therapy is a promising solution as it has been shown to prevent inflammation in the heart                                                   and reduce infarct size.  

 Photobiomodulation has been shown to be a safe and effective treatment for lung inflammation and related conditions, including acute lung injury (ALI), pulmonary fibrosis, complications associated with infections, allergic pulmonary inflammation, and asthma.  Photobiomodulation can attenuate the inflammatory response and has been shown to aid in the repairing of pulmonary tissue, which has pronounced significance due to the number of individuals experiencing complications such as acute lung injury brought on by COVID-19.  

Photobiomodulation therapy has been shown to have much promise as an effective treatment strategy to manage Chemotherapy-Induced Peripheral Neuropathy (CIPN), a toxic side effect of chemotherapy.  An estimated 20-68% of chemotherapy patients experience CIPN, with estimates varying between studies, in part due to CIPN being potentially under-reported by patients as they deal with the after-effects of cancer.  In 2021, there were 18 million new cases of cancer diagnosed worldwide, with an estimated millions of new patients suffering from CIPN annually. CIPN can take the form of numbness, paresthesia, pain, chronic peripheral neuropathy, impairment in vision or hearing, constipation, deep tendon reflex impairment, burning, autonomic dysfunction or motor and autonomic changes. CIPN can severely damage a patient’s quality of life, and mitigation of CIPN symptoms include a reduction in a patient's chemotherapy dosing or a cessation of treatment, which may increase the likelihood of mortality. Studies have shown that photobiomodulation may be able to reduce and even reverse the symptoms of CIPN [4], which may both increase the quality of life of patients and potentially decrease the cancer morbidity rate.